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Antifungal Pharmaceutical Raw Material Pure Ketoconazole Powder CAS 65277 42 1

Basic Information
Place of Origin: China
Brand Name: Sengmei
Certification: ISO
Model Number: ketoconazole powder
Minimum Order Quantity: 25 kg
Price: USD 106~140/kg
Packaging Details: 1kg/bag;25kg/Durm
Delivery Time: 1-3work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg per Month
Detail Information
Name: Ketoconazole Powder CAS: 65277-42-1
EINECS: 265-667-4 Solubility: Methanol: Soluble50mg/mL
Density: 1.4046 (rough Estimate)
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Product Description

Top grade pure ketoconazole for dogs CAS 65277-42-1 in lowest price

Ketoconazole Description

Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet.

 

Ketoconazole Function

Ketoconazole is an imidazole antifungal agent. Its mechanism of action is to inhibit the biosynthetic of ergosterol in the fungal cell membrane, affect the permeability of the cell membrane, and inhibit its growth. Ketoconazole can be used to treat superficial and deep mycosis, such as skin and onychomycosis, vaginal candidiasis, gastrointestinal fungal infections, and systemic infections caused by candida albicans, coccidioides, and histoplasmosis

Ketoconazole Application
Systemic fungal infections such as systemic candidiasis, candida paraspora, histoplasmosis, coccidioidomycosis, and blastomycosis.
Infection of skin, hair and fingers caused by dermatophytes and/or yeasts (skin fungal disease, hyperthyroidism, candida alkyditis, tinea versicolor, scalp rash, vaginal folliculitis and chronic skin) Mucosal candidiasis, etc.), when local treatment is ineffective or due to factors such as the location, area and depth of infection, can be used for treatment.
Chronic, recurrent vaginal candidiasis with local treatment ineffective.
It is used to prevent and treat patients who are prone to fungal infections due to reduced immune function (hereditary and caused by disease or drugs).
Ketoconazole Specification
PRODUCT NAME Ketoconazole
Batch number ACT20180107 Quantity 56kg
Storage Store in a well-closed container away from moisture
Items of analysis Specification Results
Appearance White or or almost white crystalline powder Conforms
Identification IR Conforms
Melting range 148.0~152.0 °C 149.8 °C
Specific Rotation -1~+1°
Loss on Drying ≤0.5% 0.24%
Residue on Ignition ≤0.1% 0.05%
Heavy Metals ≤0.002% 0.0005%
Chromatographic purity ≤ 2.0% 1.02%
Related substances ≤2.0% 0.86%
Dimethyl sulfoxide ≤ 0.50% 0.16%
Acetoacetate ≤ 0.50% 0.21%
Bacteria ≤10cfu/g 2cfu/g
Mold & yeast Negative Negative
Assay 98.0~102.0% 99.2%
Conclusion The product complies with the USP32 standard
 

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